2-(N-芳基氨甲基)苯并异噻唑啉酮类化合物对海洋浮游生物的生长抑制活性研究

doi:10.3969/j.issn.1001-909X.2015.03.007

海洋学研究 ›› 2015, Vol. 33 ›› Issue (3): 48-53.DOI: 10.3969/j.issn.1001-909X.2015.03.007

2-(N-芳基氨甲基)苯并异噻唑啉酮类化合物对海洋浮游生物的生长抑制活性研究

刘冬东^1,2,3, 施佳乐^1,2,3, 胡玥^1,2,3, 王爱明^1,2,3, 王向辉⁴, 林强⁴, 杨建新^*1,2,3

1.海南大学材料与化工学院,海南海口 570228;
2.热带生物资源教育部重点实验室,海南海口 570228;
3.海南省精细化工工程技术研究中心,海南海口 570228;
4.海南师范大学化学与化工学院, 海南海口571158

收稿日期:2015-02-03 修回日期:2015-05-06 出版日期:2015-09-15 发布日期:2022-11-28
通讯作者: *杨建新(1971-),男,教授,主要从事精细化学品的合成与分析以及荧光增白剂的合成方面的研究。E-mail:yangjxmail@sohu.com
作者简介:刘冬东(1989-),男,安徽六安市人,主要从事精细化学品的合成与分析研究。E-mail: gilliankelly@163.com
基金资助:
国家自然科学基金项目资助(20962007)

The inhibitory activities of marine plankton by 2-(N-arylaminomethyl)-3-oxo-benzo[d]isothiazoles

LIU Dong-dong^1,2,3, SHI Jia-le^1,2,3, HU Yue^1,2,3, WANG Ai-ming^1,2,3, WANG Xiang-hui⁴, LIN Qiang⁴, YANG Jian-xin^*1,2,3

1. College of Material and Chemical Engineering, Hainan University, Haikou 570228, China;
2. Key Laboratory of Tropical Biological Resources of Ministry of Education, Haikou 570228, China;
3. Hainan Provincial Fine Chemical Engineering Research Center, Haikou 570228, China;
4. College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China

Received:2015-02-03 Revised:2015-05-06 Online:2015-09-15 Published:2022-11-28

摘要/Abstract

摘要： 本文研究了13个2-(N-芳基氨甲基)苯并异噻唑啉-3-酮类化合物对球等鞭金藻Isochrysis galbana、亚心形扁藻Platymonas subcordiformis及舟形藻Navicula的生长抑制性能,并测试了其对藤壶二期无节幼虫的生物活性。结果表明:2-(N-芳基氨甲基)苯并异噻唑啉-3-酮类化合物对球等鞭金藻、亚心形扁藻和舟形藻都有良好的生长抑制活性,其中对球等鞭金藻和亚心形扁藻的抑制作用较强;对藤壶幼虫的生物活性测试表明,化合物最低质量浓度为2.0 mg/L时,除化合物g和l,都具有良好的生长抑制活性。化合物的结构与浮游生物的生长抑制活性关系表现为间位取代优于对位取代。

关键词: 苯并异噻唑啉酮, 藻类, 藤壶, 生物活性

Abstract: The growing inhibitory properties on Isochrysis galbana, Platymonas subcordiformis and Navicula of thirteen 2-(N-arylaminomethyl)-3-oxo-benzo[d]isothiazoles were investigated, and the effects on biological activity of barnacle nauplii were also studied. The results indicate that the tested compounds have favourable growing inhibitory activities to the marine algas, and the better inhibitory activities are on Isochrysis galbana and Platymonas subcordiformis. The results also indicate when the lowest concentration is 2.0 mg/L, the tested compounds show a favourable growing inhibitory activity on barnacle larvae except the compound g and l. The relationship between compounds' structure and plankton growth inhibitory activity reveals that meta-substituent is better than para-substituent.

Key words: benzoisothiazoles, algae, barnacle, biological activity

中图分类号:

TQ637.3

刘冬东, 施佳乐, 胡玥, 王爱明, 王向辉, 林强, 杨建新. 2-(N-芳基氨甲基)苯并异噻唑啉酮类化合物对海洋浮游生物的生长抑制活性研究[J]. 海洋学研究, 2015, 33(3): 48-53.

LIU Dong-dong, SHI Jia-le, HU Yue, WANG Ai-ming, WANG Xiang-hui, LIN Qiang, YANG Jian-xin. The inhibitory activities of marine plankton by 2-(N-arylaminomethyl)-3-oxo-benzo[d]isothiazoles[J]. Journal of Marine Sciences, 2015, 33(3): 48-53.

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2-(N-芳基氨甲基)苯并异噻唑啉酮类化合物对海洋浮游生物的生长抑制活性研究

The inhibitory activities of marine plankton by 2-(N-arylaminomethyl)-3-oxo-benzo[d]isothiazoles

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